Amikhelline
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Amikhelline is an antimitotic drug.[1] It acts as a DNA intercalator[2] and inhibits DNA polymerase.[3]
References[edit | edit source]
- ↑ Turchini MF, Geneix A, Perissel B, Malet P, Turchini JP. Characterization of chromosomal aberrations induced in man by various antimitotic agents. (French). Comptes Rendus des Seances de la Societe de Biologie et de ses Filiales. 1985;179(3):331-9. PMID 2417673
- ↑ Rucheton M, Jeanteur P. Studies on amikhellin. I. Intercalative binding to double-stranded DNA. Biochimie. 1973;55(11):1415-20. PMID 4364376
- ↑ Rucheton M, Jeanteur P. Studies on amikhellin. II.-Inhibition of dna-polymerase from murine sarcoma leukemia virus. Biochimie. 1976;58(6):689-95. PMID 60141
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Contributors: Prab R. Tumpati, MD
