Anexsia

Anexsia is a prescription medication that combines hydrocodone and acetaminophen. It is primarily used for the relief of moderate to severe pain. Hydrocodone is an opioid analgesic, while acetaminophen is a less potent pain reliever that increases the effects of hydrocodone.

Medical Uses

Anexsia is prescribed for the management of moderate to severe pain where the use of an opioid analgesic is appropriate. It is often used when other pain relief measures, such as non-opioid analgesics, are insufficient.

Mechanism of Action

Hydrocodone works by binding to the opioid receptors in the brain and spinal cord, which blocks the transmission of pain signals. Acetaminophen, on the other hand, works by inhibiting the synthesis of prostaglandins in the central nervous system and through a peripheral action by blocking pain-impulse generation.

Side Effects

Common side effects of Anexsia include:

• Drowsiness
• Dizziness
• Nausea
• Vomiting
• Constipation

Serious side effects may include:

• Respiratory depression
• Severe hypotension
• Hepatotoxicity (due to acetaminophen)

Contraindications

Anexsia should not be used in patients with:

• Severe respiratory depression
• Acute or severe bronchial asthma
• Known hypersensitivity to hydrocodone, acetaminophen, or any other component of the product

Drug Interactions

Anexsia can interact with other medications, including:

• Other opioids
• Benzodiazepines
• MAO inhibitors
• Anticholinergic drugs

Dosage and Administration

The dosage of Anexsia should be adjusted according to the severity of the pain and the response of the patient. It is important to follow the prescribing physician's instructions and not to exceed the recommended dose to avoid the risk of overdose and serious side effects.

Warnings and Precautions

• Anexsia has a high potential for abuse and addiction.
• It should be used with caution in patients with a history of substance abuse.
• Prolonged use during pregnancy can result in neonatal opioid withdrawal syndrome.

Related Pages

• Hydrocodone
• Acetaminophen
• Opioid
• Pain management
• Analgesic