Angiomyofibroblastoma

From WikiMD's Wellness Encyclopedia

Angiomyofibroblastoma is an uncommon benign mesenchymal tumor. It occurs almost in the vulvovaginal area of women, but can also be observed in men.

The gross features of AMFB are well-circumscribed. Usually, most tumors grow slowly, and patients do not feel pain. It also has low tendency for local recurrence.

Location[edit | edit source]

Pathology[edit | edit source]

Microscopical examination shows abundant thin-walled blood vessels with hypocellular and hypercellular areas.

Immunohistochemistry[edit | edit source]

Almost all tumor cells have immunoreactivity for both desmin and vimentin. It also express estrogen receptors and/or progesterone receptors, but staining for cytokeratin is negative.[5]

References[edit | edit source]

Contributors: Prab R. Tumpati, MD