Anorectic

An anorectic or anorexigenic is a type of drug that reduces appetite, resulting in lower food consumption, leading to weight loss. These drugs are commonly used in the treatment of obesity and are often prescribed as part of a comprehensive weight loss program that includes diet and exercise.

Mechanism of Action

Anorectics work by influencing the central nervous system to suppress appetite. They typically act on neurotransmitters such as serotonin, norepinephrine, and dopamine to create a feeling of fullness or satiety. Some common mechanisms include:

• Increasing the release of neurotransmitters
• Inhibiting the reuptake of neurotransmitters
• Mimicking the action of neurotransmitters

Types of Anorectics

There are several types of anorectics, including:

• Amphetamines: These stimulate the release of norepinephrine and dopamine.
• Serotonin Reuptake Inhibitors: These increase the levels of serotonin in the brain.
• Sympathomimetic Amines: These mimic the action of neurotransmitters like norepinephrine.

Common Anorectic Drugs

Some commonly prescribed anorectic drugs include:

• Phentermine
• Diethylpropion
• Lorcaserin
• Sibutramine (withdrawn from the market in many countries due to safety concerns)

Side Effects

Anorectics can have a range of side effects, including:

• Insomnia
• Increased heart rate
• High blood pressure
• Dry mouth
• Constipation
• Nervousness

Regulation and Safety

Due to their potential for abuse and side effects, many anorectics are classified as controlled substances in various countries. They are typically prescribed for short-term use and under strict medical supervision.

History

The use of anorectics dates back to the early 20th century, with the introduction of amphetamines. Over the years, various drugs have been developed, some of which have been withdrawn from the market due to safety concerns.

See Also

• Obesity
• Dieting
• Weight loss
• Appetite suppressant
• Central nervous system
• Neurotransmitter

Related Pages

• Phentermine
• Diethylpropion
• Lorcaserin
• Sibutramine
• Obesity
• Dieting
• Weight loss
• Appetite suppressant
• Central nervous system
• Neurotransmitter