Apraclonidine hydrochloride

Apraclonidine Hydrochloride is a medication primarily used in the field of ophthalmology. It is a synthetic analogue of clonidine and is known for its ability to decrease the production of aqueous humor in the eye, thereby reducing intraocular pressure.

Pharmacology

Apraclonidine Hydrochloride works by stimulating the alpha-2 adrenergic receptor in the ciliary body of the eye. This stimulation results in a decrease in the production of aqueous humor, which in turn reduces intraocular pressure. This makes it an effective treatment for conditions such as glaucoma and ocular hypertension.

Uses

Apraclonidine Hydrochloride is primarily used in the treatment of glaucoma and ocular hypertension. It can also be used to prevent or treat increases in intraocular pressure that may occur as a result of laser eye surgery.

Side Effects

Like all medications, Apraclonidine Hydrochloride can have side effects. These can include dry mouth, blurred vision, and fatigue. In rare cases, it can cause more serious side effects such as bradycardia or hypotension.

Contraindications

Apraclonidine Hydrochloride should not be used by individuals who are allergic to it or to any other alpha-2 adrenergic agonists. It should also be used with caution in individuals with severe cardiovascular disease or cerebrovascular disease.

See Also

• Glaucoma
• Ocular hypertension
• Alpha-2 adrenergic receptor
• Clonidine

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