Azipramine
Azipramine is a tricyclic antidepressant (TCA) that was developed in the 1960s but was never marketed. It is structurally related to other tricyclic antidepressants such as imipramine and desipramine.
Pharmacology[edit | edit source]
Azipramine acts primarily as a serotonin-norepinephrine reuptake inhibitor (SNRI), increasing the levels of serotonin and norepinephrine in the brain by inhibiting their reuptake into neurons. This results in an increase in the concentration of these neurotransmitters in the synaptic cleft, leading to increased neurotransmission.
Azipramine also has significant anticholinergic effects, which can lead to side effects such as dry mouth, constipation, urinary retention, and blurred vision. It also has antihistamine effects, which can lead to sedation.
Clinical Use[edit | edit source]
Despite its development, Azipramine was never marketed for use in any country. It is not currently approved for any medical uses. However, it has been studied in clinical trials for the treatment of various psychiatric disorders, including major depressive disorder and anxiety disorders.
Side Effects[edit | edit source]
The side effects of Azipramine are similar to those of other tricyclic antidepressants. These can include dry mouth, constipation, urinary retention, blurred vision, and sedation. More serious side effects can include cardiac arrhythmias, orthostatic hypotension, and seizures.
See Also[edit | edit source]
 | This pharmacology-related article is a stub. You can help WikiMD by expanding it. |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
