B-cell lymphomas

B-cell lymphomas are a type of cancer that forms in B cells. B cells are a type of white blood cell that are vital to the immune system and are responsible for producing antibodies to fight off infections. B-cell lymphomas can occur in both children and adults, and are often categorized as either Hodgkin lymphoma or non-Hodgkin lymphoma.

Types of B-cell lymphomas

There are several types of B-cell lymphomas, including:

• Diffuse large B-cell lymphoma (DLBCL): This is the most common type of non-Hodgkin lymphoma in adults. It is an aggressive form of lymphoma that can occur at any age, but it is most common in adults over the age of 60.

• Follicular lymphoma: This is the second most common type of non-Hodgkin lymphoma. It is a slow-growing form of lymphoma that often presents with painless swelling in the lymph nodes.

• Mantle cell lymphoma: This is a rare type of non-Hodgkin lymphoma that is typically aggressive and fast-growing. It is most common in older adults, particularly men.

• Burkitt lymphoma: This is a very aggressive form of non-Hodgkin lymphoma that is most common in children and young adults. It is associated with a specific genetic mutation.

Symptoms

The symptoms of B-cell lymphomas can vary depending on the type and stage of the disease, but common symptoms include:

• Swollen, painless lymph nodes in the neck, armpit, or groin
• Unexplained weight loss
• Fatigue
• Night sweats
• Fever

Diagnosis

Diagnosis of B-cell lymphomas typically involves a physical examination, medical history, and a biopsy of the affected lymph node or tissue. Additional tests may include blood tests, imaging studies such as a CT scan or PET scan, and a bone marrow biopsy.

Treatment

Treatment for B-cell lymphomas depends on the type and stage of the disease, as well as the patient's overall health. Treatment options may include chemotherapy, radiation therapy, immunotherapy, targeted therapy, or a combination of these. In some cases, a stem cell transplant may be recommended.

See also

• Lymphoma
• Cancer
• Chemotherapy
• Radiation therapy