Ethinylestradiol/cyproterone acetate

Ethinylestradiol/cyproterone acetate is a combination of ethinylestradiol, an estrogen, and cyproterone acetate, an antiandrogen and progestogen. It is an oral contraceptive that is used widely in the treatment of androgen-dependent conditions like acne, seborrhea, hirsutism, and androgenic alopecia in women.

Etymology

The term "ethinylestradiol" is derived from the words "ethynyl" and "estradiol". "Ethynyl" refers to the presence of a triple bond between two carbon atoms, while "estradiol" is a type of estrogen, a hormone that plays a key role in the female reproductive system. "Cyproterone acetate" is named after its two components: "cyproterone", an antiandrogen and progestogen, and "acetate", a salt or ester of acetic acid.

Pharmacology

Ethinylestradiol is a synthetic estrogen that is more potent than natural estrogens. It works by inhibiting the release of gonadotropins, which in turn prevents ovulation. Cyproterone acetate is a derivative of progesterone and has antiandrogenic properties. It works by blocking the effects of androgens in the body, which can help to reduce symptoms of androgen-dependent conditions.

Uses

Ethinylestradiol/cyproterone acetate is primarily used as an oral contraceptive. It is also used in the treatment of androgen-dependent conditions in women, such as acne, seborrhea, hirsutism, and androgenic alopecia. In addition, it can be used in the treatment of polycystic ovary syndrome (PCOS), a condition characterized by high levels of androgens and irregular menstrual periods.

Side Effects

Like all medications, ethinylestradiol/cyproterone acetate can cause side effects. These may include nausea, vomiting, headache, breast tenderness, changes in menstrual periods, and mood changes. In rare cases, it can cause serious side effects such as blood clots, liver problems, and allergic reactions.

See Also

• Oral contraceptive
• Estrogen
• Antiandrogen
• Progestogen
• Androgen-dependent condition
• Polycystic ovary syndrome

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