Bence Jones protein
Introduction[edit | edit source]
Bence Jones protein (pronounced bents jones PROH-teen) is a specific protein associated with certain medical conditions, most notably multiple myeloma. It is an important biomarker used in the diagnosis and monitoring of specific types of blood disorders and cancers.
Discovery and Naming[edit | edit source]
The protein was first identified by Dr. Henry Bence Jones in 1847 when he discovered its presence in the urine of a patient with a peculiar form of bone disease. The protein was subsequently named in his honor.
Production and Composition[edit | edit source]
Bence Jones proteins are small proteins produced by plasma cells. Plasma cells are a type of white blood cell responsible for producing antibodies that help the body fight infections.
Association with Multiple Myeloma[edit | edit source]
The presence of Bence Jones protein in urine is a significant marker for multiple myeloma, a type of cancer that originates in plasma cells. Multiple myeloma leads to an overproduction of these proteins, which are then excreted in the urine.
- Detection: The detection of Bence Jones proteins is done through a urine test. The presence of these proteins in significant quantities can be an early indicator of multiple myeloma or other related conditions.
- Significance: Beyond diagnosis, the levels of Bence Jones proteins can also be used to monitor the progression of the disease and the effectiveness of treatments.
Other Associated Conditions[edit | edit source]
While most commonly associated with multiple myeloma, Bence Jones proteins can also be found in patients with other conditions, including:
- Waldenström's macroglobulinemia
- Certain subtypes of lymphoma
- Other plasma cell disorders
Conclusion[edit | edit source]
Bence Jones proteins play a crucial role in the diagnosis and management of multiple myeloma and related conditions. Their discovery has significantly advanced the field of hematology, providing valuable insights into plasma cell disorders and improving patient outcomes.
| Bence Jones protein Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Kondreddy Naveen
