Benzamide
Benzamide is an organic compound with the chemical formula C7H7NO. It is a derivative of benzoic acid with an amide functional group replacing the hydroxyl group. Benzamide is a white, crystalline solid that is slightly soluble in water and more so in organic solvents such as ethanol and diethyl ether. It is used in the synthesis of various pharmaceuticals and as an intermediate in the production of dyes and other organic compounds.
Structure and Properties[edit | edit source]
Benzamide consists of a benzene ring attached to a carboxamide group. The presence of the amide group significantly affects the chemical and physical properties of the compound. The amide group forms hydrogen bonds, which are responsible for the higher melting point of benzamide compared to its parent compound, benzoic acid. The ability to form hydrogen bonds also influences its solubility in water and other polar solvents.
Synthesis[edit | edit source]
Benzamide can be synthesized through several methods. One common approach is the direct amidation of benzoic acid with ammonia or an amine in the presence of a dehydrating agent. Another method involves the reaction of benzoyl chloride with ammonia or an amine. These methods allow for the production of benzamide under relatively mild conditions.
Applications[edit | edit source]
Benzamide and its derivatives are used in a wide range of applications. In the pharmaceutical industry, benzamide derivatives are explored for their potential therapeutic properties. Some derivatives have been studied for their anticonvulsant, anti-inflammatory, and antipsychotic activities. Additionally, benzamide is used as a building block in organic synthesis, including the preparation of various dyes, plastics, and other advanced materials.
Safety and Toxicology[edit | edit source]
Benzamide is generally considered to have low toxicity. However, like all chemicals, it should be handled with care, and appropriate safety measures should be taken to avoid ingestion, inhalation, or skin contact. Material safety data sheets (MSDS) provide detailed information on handling, storage, and emergency measures.
See Also[edit | edit source]
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
