Benzphetamine hydrochloride

Benzphetamine Hydrochloride is a prescription medication classified as an anorectic or anorexigenic drug. It is primarily used in the treatment of obesity and is marketed under the brand name Didrex by Pharmacia. Benzphetamine Hydrochloride is a sympathomimetic amine, which is similar to an amphetamine. It is also classified as a Schedule III controlled substance under the Controlled Substances Act in the United States due to its potential for misuse and addiction.

Pharmacology

Benzphetamine Hydrochloride works by stimulating the central nervous system, which increases heart rate and blood pressure, and decreases appetite. It is thought to work by triggering the release of norepinephrine in the brain, a neurotransmitter that signals feelings of satiety.

Medical Uses

Benzphetamine Hydrochloride is used as a short-term supplement in a regimen of weight reduction based on exercise, behavioral modification, and caloric restriction in the management of exogenous obesity for patients with an initial body mass index (BMI) of 30 kg/m² or higher and who have not responded to appropriate weight reducing regimen (diet and/or physical activity) alone.

Side Effects

Common side effects of Benzphetamine Hydrochloride include restlessness, nervousness, and difficulty sleeping. More serious side effects can include increased blood pressure, heart palpitations, and changes in libido. Long-term use can lead to dependency and withdrawal symptoms upon cessation.

Contraindications

Benzphetamine Hydrochloride is contraindicated in individuals with a history of cardiovascular disease, severe hypertension, hyperthyroidism, glaucoma, drug abuse, and hypersensitivity to sympathomimetic amines.

See Also

• Phentermine
• Amphetamine
• Anti-obesity medication