Biconcave disc
Biconcave disc is a term used in anatomy and physiology to describe the shape of certain cells or structures within the body. The most notable example of a biconcave disc is the red blood cell (RBC), also known as an erythrocyte.
Structure[edit | edit source]
A biconcave disc is a disc that is concave, or curved inward, on both sides. This shape allows for a larger surface area relative to volume, which is beneficial for cells like the red blood cell that need to maximize the exchange of gases.
Red Blood Cells[edit | edit source]
Red blood cells are the most common example of biconcave discs. They are approximately 7.5 micrometers in diameter and have a thickness of 2 micrometers at the thickest point and 1 micrometer at the thinnest point. The biconcave shape provides a large surface area to volume ratio, which facilitates the exchange of oxygen and carbon dioxide with the surrounding environment.
Function[edit | edit source]
The primary function of the biconcave shape in red blood cells is to increase the surface area for gas exchange. The larger surface area allows for more efficient diffusion of oxygen and carbon dioxide. This shape also allows the cells to deform and pass through the smallest capillaries.
Clinical significance[edit | edit source]
Changes in the shape of red blood cells can indicate certain medical conditions. For example, in sickle cell anemia, red blood cells become sickle-shaped instead of biconcave, which can lead to various complications.
See also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD