Bimakalim

Bimakalim is a vasodilator and potassium channel opener that has been studied for potential use in the treatment of hypertension and angina pectoris. It is not currently approved for use in humans.

Mechanism of action[edit | edit source]

Bimakalim acts by opening ATP-sensitive potassium channels in the smooth muscle of blood vessels. This causes the muscle to relax, leading to vasodilation and a decrease in blood pressure.

Pharmacokinetics[edit | edit source]

The pharmacokinetics of bimakalim are not well studied. It is known to be metabolized in the liver and excreted in the urine.

Clinical trials[edit | edit source]

Bimakalim has been studied in clinical trials for the treatment of hypertension and angina pectoris. However, it has not been approved for use in humans due to concerns about its safety and efficacy.

Side effects[edit | edit source]

Potential side effects of bimakalim include hypotension, dizziness, and headache. More serious side effects may include cardiac arrhythmia and hypokalemia.

See also[edit | edit source]

Bimakalim Resources
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