Breast cancer risk factors

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Breast Cancer Risk Factors

Breast cancer is a complex disease with multiple risk factors. Some of these factors are modifiable, meaning they can be changed, while others are non-modifiable and cannot be altered. Understanding these risk factors is crucial for early detection and prevention strategies.

Non-Modifiable Risk Factors[edit | edit source]

  • Age: The risk of developing breast cancer increases with age. Most cases are diagnosed in women over 50 years of age.
  • Genetics: About 5-10% of breast cancer cases are thought to be hereditary, caused by abnormal genes passed from parent to child. The most common genes associated with breast cancer are BRCA1 and BRCA2.
  • Family History: Having a first-degree relative (mother, sister, or daughter) with breast cancer doubles a woman's risk.
  • Personal History of Breast Cancer: Women who have had breast cancer are more likely to develop a new cancer in the other breast or another part of the same breast.
  • Dense Breast Tissue: Women with dense breasts have a higher risk of breast cancer. Dense breast tissue can also make it harder for mammograms to detect breast cancer.
  • Gender: Being a woman is the main risk factor for developing breast cancer. Men can get breast cancer, but it is about 100 times more common among women.
  • Race and Ethnicity: In the United States, white women are slightly more likely to develop breast cancer than African American women. However, African American women are more likely to die of the disease.

Modifiable Risk Factors[edit | edit source]

  • Alcohol Consumption: The more alcohol a woman drinks, the greater her risk of breast cancer.
  • Obesity: Being overweight or obese increases the risk of breast cancer, especially after menopause.
  • Physical Activity: Being physically inactive can increase the risk of breast cancer.
  • Reproductive History: Having no children or having your first child after age 30 increases the risk of breast cancer. Breastfeeding can lower the risk.
  • Hormone Replacement Therapy (HRT): Long-term use of HRT, especially combined estrogen-progestin therapy, can increase the risk of breast cancer.
  • Oral Contraceptives: Some studies have found that women who use oral contraceptives have a slightly higher risk of breast cancer than women who have never used them.

Prevention and Screening[edit | edit source]

While not all risk factors are within one's control, lifestyle changes such as reducing alcohol consumption, maintaining a healthy weight, and increasing physical activity can help lower the risk of developing breast cancer. Regular screening and mammograms can also aid in early detection, which is crucial for successful treatment.

See Also[edit | edit source]


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Contributors: Prab R. Tumpati, MD