Bromopride

Bromopride

Bromopride is a dopamine antagonist with prokinetic properties widely used as an antiemetic, similar to metoclopramide or domperidone. It is manufactured and marketed by several different pharmaceutical companies.

Pharmacology

Bromopride is a derivative of metoclopramide and is classified as a dopamine antagonist. It works by blocking dopamine receptors in the brain, which helps to control nausea and vomiting. In addition, it has prokinetic properties, meaning it helps to speed up the movement of food through the stomach and intestines, which can help to relieve symptoms of gastrointestinal disorders.

Uses

Bromopride is primarily used to treat nausea and vomiting, including that caused by chemotherapy, radiation therapy, surgery, and certain medications. It is also used to treat gastrointestinal disorders such as gastroparesis, gastroesophageal reflux disease (GERD), and irritable bowel syndrome (IBS).

Side Effects

Like all medications, Bromopride can cause side effects. Common side effects include drowsiness, fatigue, diarrhea, and headache. Less common but more serious side effects can include tardive dyskinesia, a condition characterized by involuntary movements, particularly of the face.

Contraindications

Bromopride should not be used by individuals with pheochromocytoma, a rare tumor of the adrenal gland, as it may cause a severe increase in blood pressure. It is also contraindicated in individuals with gastrointestinal bleeding, obstruction, or perforation.

See Also

• Dopamine antagonist
• Prokinetic agent
• Antiemetic
• Metoclopramide
• Domperidone