CCR10

CCR10 is a gene that encodes the Chemokine receptor CCR10 in humans. This receptor is a member of the G protein-coupled receptor family. The ligands for this receptor are the chemokines CCL27 and CCL28.

Function

CCR10 and its ligands play a role in skin homeostasis and inflammation. They are involved in the migration of memory T cells to the skin during an inflammatory response.

Clinical significance

Mutations in the CCR10 gene have been associated with various diseases, including psoriasis, atopic dermatitis, and melanoma.

See also

• Chemokine receptor
• G protein-coupled receptor
• CCL27
• CCL28

External links

• CCR10 at the National Center for Biotechnology Information

CCR10 Resources
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