CHRNA2
CHRNA2 is a gene that encodes the alpha-2 subunit of the nicotinic acetylcholine receptor (nAChR). The nAChR is a type of ionotropic receptor that is activated by the neurotransmitter acetylcholine. The CHRNA2 gene is located on the long arm of chromosome 8 (8q21.3).
Function[edit | edit source]
The CHRNA2 gene is part of a family of genes that encode the subunits of the nicotinic acetylcholine receptors. These receptors are found in the central nervous system and play a crucial role in neurotransmission. The alpha-2 subunit encoded by the CHRNA2 gene is one of several different subunits that can combine to form a functional nAChR. The specific combination of subunits determines the receptor's functional properties, such as its sensitivity to different neurotransmitters and drugs.
Clinical significance[edit | edit source]
Mutations in the CHRNA2 gene have been associated with a variety of neurological disorders. For example, a rare mutation in this gene has been linked to autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE), a form of epilepsy characterized by nocturnal seizures that originate in the frontal lobe of the brain. Other studies have suggested a possible association between variations in the CHRNA2 gene and susceptibility to nicotine addiction and schizophrenia, although more research is needed to confirm these findings.
See also[edit | edit source]
References[edit | edit source]
Transform your life with W8MD's budget GLP1 injections from $125 and up biweekly
W8MD offers a medical weight loss program NYC and a clinic to lose weight in Philadelphia. Our W8MD's physician supervised medical weight loss centers in NYC provides expert medical guidance, and offers telemedicine options for convenience.
Why choose W8MD?
- Comprehensive care with FDA-approved weight loss medications including:
- loss injections in NYC both generic and brand names:
- weight loss medications including Phentermine, Qsymia, Contrave, Diethylpropion etc.
- Accept most insurances for visits or discounted self pay cost.
- Generic weight loss injections starting from just $125.00 for the starting dose
- In person weight loss NYC and telemedicine medical weight loss options in New York city available
Book Your Appointment
Start your NYC weight loss journey today at our NYC medical weight loss, and Philadelphia and visit Philadelphia medical weight loss Call (718)946-5500 for NY and 215 676 2334 for PA
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's NYC physician weight loss.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available. Call 718 946 5500.
Advertise on WikiMD
WikiMD's Wellness Encyclopedia |
Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD