CMV polyradiculomyelopathy
CMV Polyradiculomyelopathy | |
---|---|
Synonyms | N/A |
Pronounce | N/A |
Specialty | N/A |
Symptoms | Weakness, sensory loss, urinary retention |
Complications | Paralysis, bladder dysfunction |
Onset | Immunocompromised individuals |
Duration | Variable |
Types | N/A |
Causes | Cytomegalovirus infection |
Risks | HIV/AIDS, organ transplantation |
Diagnosis | Lumbar puncture, MRI, PCR testing |
Differential diagnosis | N/A |
Prevention | N/A |
Treatment | Antiviral therapy, supportive care |
Medication | N/A |
Prognosis | Variable |
Frequency | N/A |
Deaths | N/A |
CMV Polyradiculomyelopathy is a neurological disorder caused by infection with the Cytomegalovirus (CMV), primarily affecting the spinal cord and nerve roots. It is most commonly seen in immunocompromised individuals, such as those with HIV/AIDS or those who have undergone organ transplantation.
Signs and Symptoms[edit | edit source]
Patients with CMV Polyradiculomyelopathy typically present with weakness, sensory loss, and urinary retention. These symptoms are due to the inflammation and damage to the nerve roots and spinal cord. In severe cases, paralysis and bladder dysfunction may occur.
Causes[edit | edit source]
The condition is caused by the reactivation of Cytomegalovirus in individuals with weakened immune systems. CMV is a common virus that can remain dormant in the body and reactivate when the immune system is compromised.
Diagnosis[edit | edit source]
Diagnosis of CMV Polyradiculomyelopathy involves a combination of clinical evaluation and diagnostic tests. A lumbar puncture may be performed to analyze the cerebrospinal fluid for signs of infection. MRI of the spine can reveal inflammation of the nerve roots. PCR testing of the cerebrospinal fluid can confirm the presence of CMV DNA.
Treatment[edit | edit source]
Treatment typically involves antiviral therapy with medications such as ganciclovir or foscarnet. Supportive care is also important to manage symptoms and prevent complications.
Prognosis[edit | edit source]
The prognosis for CMV Polyradiculomyelopathy varies depending on the severity of the condition and the patient's overall health. Early diagnosis and treatment can improve outcomes, but some patients may experience long-term neurological deficits.
See Also[edit | edit source]
References[edit | edit source]
External Links[edit | edit source]
- [CDC on Cytomegalovirus](https://www.cdc.gov/cmv/index.html)
- [HIV.gov on Opportunistic Infections](https://www.hiv.gov/hiv-basics/staying-in-hiv-care/other-related-health-issues/opportunistic-infections)
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