CXCR6

CXCR6 is a gene that in humans is encoded by the CXCR6 gene. It is also known as Bonzo, STRL33 and TYMSTR, and is a member of the CXC chemokine receptor family.

Function

The CXCR6 gene encodes a G protein-coupled receptor that binds the chemokine CXCL16. This receptor is expressed in T cells and is known to mediate cell migration.

Clinical significance

CXCR6 has been implicated in a variety of diseases. It is overexpressed in several types of cancer, including breast cancer, prostate cancer, and colorectal cancer. In addition, it plays a role in inflammation and autoimmune diseases.

See also

• CXC chemokine receptors
• Chemokine
• G protein-coupled receptor

External links

• CXCR6 at the US National Library of Medicine Medical Subject Headings (MeSH)

CXCR6 Resources
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