Canal of hering
Canal of Hering
The Canal of Hering, also known as the bile preductule or cholangiole, is a part of the outflow system of exocrine bile product from the liver in many species, including humans. These canals are named after the German anatomist, Eduard Friedrich Wilhelm Hering, who first described them in the 19th century.
Anatomy and Function[edit | edit source]
The Canal of Hering is located in the periportal portion of the liver lobule. It represents the transition between the hepatocyte-lined Canaliculi and the cholangiocyte-lined Bile duct. The canal is lined by a simple cuboidal epithelium which is a mixture of hepatocytes and cholangiocytes.
The primary function of the Canal of Hering is to transport bile, produced by hepatocytes, to the bile ducts. This is a crucial part of the liver's function in digestion, as bile is necessary for the breakdown and absorption of fats.
Clinical Significance[edit | edit source]
The Canal of Hering is of particular interest in the field of Hepatology, as it is believed to be the site of origin of a significant proportion of primary liver cancers, known as Cholangiocarcinoma. It is also the location of the liver's stem cells, which play a key role in liver regeneration.
Damage to the Canal of Hering, such as through cholangitis or other liver diseases, can disrupt the flow of bile and lead to serious health complications, including Cirrhosis and Liver failure.
See Also[edit | edit source]
References[edit | edit source]
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