Chloroacetaldehyde
Chloroacetaldehyde is an organic compound with the formula ClCH2CHO. This compound is a colorless liquid with a pungent odor. It is a versatile reagent in organic synthesis and a building block in the synthesis of pharmaceuticals.
Structure and Properties[edit | edit source]
Chloroacetaldehyde consists of a vinyl group, which is a type of functional group in organic chemistry, and a chlorine atom. The molecule is polar due to the electronegativity difference between the chlorine and hydrogen atoms. This polarity contributes to its reactivity in organic synthesis.
Synthesis[edit | edit source]
Chloroacetaldehyde can be synthesized through the oxidation of vinyl chloride, a colorless gas with a mild, sweet odor. This process involves the use of a strong oxidizing agent, such as chromic acid or potassium permanganate.
Uses[edit | edit source]
Chloroacetaldehyde is primarily used as a building block in the synthesis of pharmaceuticals. It is also used in the production of dyes, perfumes, and resins. In addition, it serves as a reagent in organic synthesis, where it is used to introduce the 2-chloroacetyl group.
Safety[edit | edit source]
Exposure to chloroacetaldehyde can cause irritation to the eyes, skin, and respiratory tract. It is also classified as a potential carcinogen by the International Agency for Research on Cancer (IARC). Therefore, proper safety measures should be taken when handling this compound.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD