Chloroacetaldehyde

Chloroacetaldehyde is an organic compound with the formula ClCH2CHO. This compound is a colorless liquid with a pungent odor. It is a versatile reagent in organic synthesis and a building block in the synthesis of pharmaceuticals.

Structure and Properties

Chloroacetaldehyde consists of a vinyl group, which is a type of functional group in organic chemistry, and a chlorine atom. The molecule is polar due to the electronegativity difference between the chlorine and hydrogen atoms. This polarity contributes to its reactivity in organic synthesis.

Synthesis

Chloroacetaldehyde can be synthesized through the oxidation of vinyl chloride, a colorless gas with a mild, sweet odor. This process involves the use of a strong oxidizing agent, such as chromic acid or potassium permanganate.

Uses

Chloroacetaldehyde is primarily used as a building block in the synthesis of pharmaceuticals. It is also used in the production of dyes, perfumes, and resins. In addition, it serves as a reagent in organic synthesis, where it is used to introduce the 2-chloroacetyl group.

Safety

Exposure to chloroacetaldehyde can cause irritation to the eyes, skin, and respiratory tract. It is also classified as a potential carcinogen by the International Agency for Research on Cancer (IARC). Therefore, proper safety measures should be taken when handling this compound.

See Also

• Vinyl chloride
• Organic synthesis
• Oxidation