Iocetamic acid
(Redirected from Cholebrine)
Iocetamic acid holds a prominent position in the world of diagnostic radiology. An organoiodine compound, this molecule has found widespread application as a contrast medium, enhancing the clarity and precision of radiographic images.
Chemical and Structural Features[edit | edit source]
Iocetamic acid, much like other iodinated contrast agents, is characterized by the presence of iodine moieties within its molecular structure. The ability of iodine to absorb X-rays efficiently means that, once introduced into the human body, iocetamic acid provides enhanced contrast on radiographic images, delineating structures with varying densities[1].
Diagnostic Applications[edit | edit source]
Owing to its radiopaque properties, iocetamic acid is used in a variety of imaging studies, such as:
Its ability to enhance contrast allows for the differentiation of various body tissues, leading to clearer images that enable precise medical diagnoses[2].
Pharmacokinetics and Distribution[edit | edit source]
Upon administration, iocetamic acid swiftly disperses within the vascular and interstitial compartments. Its renal excretion ensures that the molecule is cleared from the body after its diagnostic purpose has been served. However, special attention must be accorded to patients with compromised kidney function, as adjustments in dosage might be necessary[3].
Safety and Adverse Reactions[edit | edit source]
In general, iocetamic acid is well-tolerated, but, as with other contrast media, there is a potential for side effects:
- Mild: Sensation of warmth, transient nausea, and flushing
- Moderate to severe: Hypersensitivity or allergic reactions, contrast-induced nephropathy
- Rare: Severe allergic reactions, cardiovascular or respiratory complications
- Clinicians should always be prepared to manage any potential adverse reactions and should obtain a thorough medical history to identify patients at elevated risk[4].
Conclusion[edit | edit source]
Iocetamic acid, owing to its distinct characteristics and proven efficacy as a contrast medium, has revolutionized the domain of diagnostic imaging. With careful patient screening and the readiness to manage adverse reactions, this contrast agent can be used safely and effectively in clinical practice.
 | This pharmacology-related article is a stub. You can help WikiMD by expanding it. |
References[edit | edit source]
Strickland, N. H. (1991). Iodinated contrast media: physical and biological properties. The British Journal of Radiology, 64(767), 923-928. Thomsen, H. S., & Morcos, S. K. (2003). Contrast media and the kidney: European Society of Urogenital Radiology (ESUR) guidelines. The British Journal of Radiology, 76(908), 513-518. Cohan, R. H., Dunnick, N. R., & Leder, R. A. (1992). Intravascular contrast material administration: guidelines for use and potential complications. Radiographics, 12(1), 173-187. Katayama, H., Yamaguchi, K., Kozuka, T., Takashima, T., & Seez, P. (1990). Adverse reactions to ionic and nonionic contrast media: a report from the Japanese Committee on the Safety of Contrast Media. Radiology, 175(3), 621-628.
- ↑ Strickland, N. H. (1991). Iodinated contrast media: physical and biological properties. The British Journal of Radiology, 64(767), 923-928.
- ↑ Thomsen, H. S., & Morcos, S. K. (2003). Contrast media and the kidney: European Society of Urogenital Radiology (ESUR) guidelines. The British Journal of Radiology, 76(908), 513-518.
- ↑ Cohan, R. H., Dunnick, N. R., & Leder, R. A. (1992). Intravascular contrast material administration: guidelines for use and potential complications. Radiographics, 12(1), 173-187.
- ↑ Katayama, H., Yamaguchi, K., Kozuka, T., Takashima, T., & Seez, P. (1990). Adverse reactions to ionic and nonionic contrast media: a report from the Japanese Committee on the Safety of Contrast Media. Radiology, 175(3), 621-628.
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
