Diatrizoic acid

Diatrizoic acid (also known as Amidotrizoic acid) is a high-osmolar contrast agent used in radiology to enhance the visibility of bodily structures in radiographic procedures. It is a type of iodinated contrast agent, which means it contains iodine atoms that can absorb X-rays and make certain tissues or structures more visible on the X-ray film.

History

Diatrizoic acid was first synthesized in the early 20th century. It was one of the first iodinated contrast agents to be used in medical imaging, and it has played a significant role in the development of modern radiology.

Chemical Structure

Diatrizoic acid is a complex organic compound that contains three iodine atoms. Its chemical formula is C11H9I3N2O4. The iodine atoms in the compound are what allow it to absorb X-rays and provide contrast in radiographic images.

Medical Use

In medical imaging, diatrizoic acid is used as a contrast agent in a variety of procedures, including CT scans, IVP, and angiograms. It can be administered orally or intravenously, depending on the type of procedure. The contrast agent helps to highlight certain areas of the body, making it easier for doctors to diagnose a range of conditions.

Side Effects

Like all contrast agents, diatrizoic acid can cause side effects in some patients. These can range from mild reactions like nausea and vomiting, to more serious reactions such as anaphylaxis. Patients with a history of allergic reactions to iodinated contrast agents are typically not given diatrizoic acid.

See Also

• Contrast (radiology)
• Iodinated contrast
• Radiology

References

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