Cilgavimab/Tixagevimab
Cilgavimab/Tixagevimab is a combination of two monoclonal antibodies designed for the prevention and treatment of COVID-19. This combination is developed by AstraZeneca, a British-Swedish multinational pharmaceutical and biopharmaceutical company.
Mechanism of Action[edit | edit source]
Cilgavimab and Tixagevimab work together to bind to different sites on the spike protein of the SARS-CoV-2 virus, preventing the virus from entering human cells. This dual action is believed to increase the effectiveness of the treatment and reduce the likelihood of the virus developing resistance.
Clinical Trials[edit | edit source]
The combination of Cilgavimab and Tixagevimab has been tested in several clinical trials. In the Phase III trials, the combination was shown to reduce the risk of severe COVID-19 and death in high-risk patients.
Approval[edit | edit source]
As of February 2022, Cilgavimab/Tixagevimab has been granted emergency use authorization by the U.S. Food and Drug Administration (FDA) and conditional marketing authorization by the European Medicines Agency (EMA).
Side Effects[edit | edit source]
Common side effects of Cilgavimab/Tixagevimab include nausea, vomiting, diarrhea, and fever. Serious side effects are rare but can include severe allergic reactions.
See Also[edit | edit source]
References[edit | edit source]
 | This medical article is a stub. You can help WikiMD by expanding it. |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
