Cingulum (brain)

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Cingulum (brain)

The Cingulum is a collection of white matter fibers projecting from the cingulate gyrus to the entorhinal cortex in the brain, forming an integral part of the limbic system. It is also involved in various cognitive functions such as attention, working memory, and emotion.

File:Cingulum (brain).jpg
The cingulum is located in the medial aspect of the brain.

Anatomy[edit | edit source]

The cingulum is a long, arched bundle of fibers curving around the corpus callosum and the cingulate gyrus. It is divided into three parts: the anterior cingulum, the posterior cingulum, and the retrosplenial cingulum. The anterior cingulum is connected to the prefrontal cortex, while the posterior cingulum is connected to the parietal lobe. The retrosplenial cingulum connects the cingulate gyrus to the hippocampus.

Function[edit | edit source]

The cingulum plays a crucial role in various cognitive and emotional functions. It is involved in attention, working memory, and emotion. It also plays a role in pain perception and has been implicated in conditions such as schizophrenia, bipolar disorder, and Alzheimer's disease.

Clinical significance[edit | edit source]

Damage to the cingulum can result in a variety of cognitive and emotional deficits. These include difficulties with attention, memory, and emotion regulation. In addition, abnormalities in the cingulum have been associated with several psychiatric and neurological disorders, including schizophrenia, bipolar disorder, and Alzheimer's disease.

See also[edit | edit source]

References[edit | edit source]


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Contributors: Prab R. Tumpati, MD