Ciprocinonide
Ciprocinonide is a synthetic corticosteroid used in the treatment of various skin conditions. It is a potent steroid and is often prescribed for severe inflammatory skin disorders, such as eczema and psoriasis. Ciprocinonide works by reducing inflammation and suppressing the immune response in the skin.
Pharmacology[edit | edit source]
Ciprocinonide is a glucocorticoid receptor agonist. It binds to the glucocorticoid receptor, leading to changes in gene expression. This results in a decrease in the production of inflammatory mediators and a reduction in the immune response. The exact mechanism of action of ciprocinonide is not fully understood, but it is believed to involve the inhibition of phospholipase A2, an enzyme involved in the production of inflammatory mediators.
Uses[edit | edit source]
Ciprocinonide is used topically to treat a variety of skin conditions, including:
It is also used to treat other conditions that cause inflammation and itching of the skin.
Side Effects[edit | edit source]
Like all corticosteroids, ciprocinonide can cause side effects. These may include:
- Skin thinning
- Stretch marks
- Skin discoloration
- Easy bruising
- Changes in skin texture
More serious side effects can occur if the medication is used for a long period of time or over a large area of the body. These can include:
- Adrenal suppression
- Cushing's syndrome
- High blood sugar
- Bone loss
Precautions[edit | edit source]
Before using ciprocinonide, patients should inform their healthcare provider if they have any other medical conditions, especially:
- Diabetes
- Poor blood circulation
- Immune system problems
Ciprocinonide should not be used on the face, underarms, or groin area unless directed by a healthcare provider. It should not be used in children under 2 years of age.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD