Cismadinone acetate

Cismadinone acetate is a steroidal progestin that is related to progesterone. It is used in hormone therapy and for the treatment of menstrual disorders and endometriosis.

Pharmacology

Cismadinone acetate is a synthetic progestin that is derived from 17α-hydroxyprogesterone. It has a high affinity for the progesterone receptor and acts as an agonist at this receptor. This results in changes in the endometrium that prepare it for implantation of a fertilized egg and maintenance of pregnancy.

Clinical use

Cismadinone acetate is used in the treatment of a variety of gynecological disorders, including dysmenorrhea, amenorrhea, and endometriosis. It is also used in hormone replacement therapy to alleviate symptoms of menopause and to prevent osteoporosis.

Side effects

Like other progestins, cismadinone acetate can cause a number of side effects. These may include nausea, bloating, breast tenderness, and changes in menstrual cycle. In rare cases, it can cause more serious side effects such as blood clots and liver damage.

See also

• Progestin
• Hormone therapy
• Endometriosis

References

‎