Clopenthixol

Clopenthixol (also known as Zuclopenthixol) is a typical antipsychotic drug from the thioxanthene group. It is primarily used in the treatment of schizophrenia and other psychotic disorders.

Pharmacology

Clopenthixol is a dopamine antagonist, which means it works by blocking the action of dopamine, a neurotransmitter in the brain that is involved in mood and behaviour. It also has some anticholinergic properties, which can help to reduce the side effects of other medications.

Uses

Clopenthixol is used in the treatment of a range of mental health conditions, including:

• Schizophrenia
• Bipolar disorder
• Psychosis
• Paranoia
• Agitation associated with these conditions

It can also be used in the management of severe anxiety and agitation in people with dementia.

Side effects

Like all medications, clopenthixol can cause side effects. These can include:

• Drowsiness
• Dry mouth
• Blurred vision
• Constipation
• Weight gain
• Tardive dyskinesia (a movement disorder)

Precautions

Before starting clopenthixol, it is important to discuss any other medications you are taking with your doctor, as it can interact with a number of other drugs. It should be used with caution in people with liver disease, heart disease, and Parkinson's disease.

See also

• Antipsychotic
• Schizophrenia
• Psychosis