Cofrogliptin

Cofrogliptin

Cofrogliptin is a pharmaceutical drug used in the treatment of Type 2 diabetes. It belongs to the class of drugs known as Dipeptidyl peptidase-4 inhibitors or DPP-4 inhibitors.

Mechanism of Action

Cofrogliptin works by inhibiting the enzyme Dipeptidyl peptidase-4 (DPP-4). This enzyme is involved in the breakdown of Incretin hormones, which are responsible for increasing the amount of insulin released by the pancreas. By inhibiting DPP-4, Cofrogliptin increases the levels of incretin hormones, leading to an increase in insulin release. This helps to lower blood glucose levels and manage the symptoms of Type 2 diabetes.

Clinical Use

Cofrogliptin is used in the management of Type 2 diabetes. It is often used in combination with other antidiabetic medications such as Metformin or Sulfonylureas. The drug is usually taken orally, once a day.

Side Effects

Like all medications, Cofrogliptin can cause side effects. Common side effects include nausea, vomiting, diarrhea, and abdominal pain. In rare cases, it can cause serious side effects such as pancreatitis and hypoglycemia.

Contraindications

Cofrogliptin is contraindicated in patients with a history of hypersensitivity to the drug or any of its components. It is also contraindicated in patients with Type 1 diabetes or diabetic ketoacidosis.

See Also

• Dipeptidyl peptidase-4 inhibitors
• Type 2 diabetes
• Incretin
• Metformin
• Sulfonylureas