Collagen-induced arthritis

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Collagen-induced arthritis (CIA) is a condition induced in mice (or rats) to study rheumatoid arthritis.^[1]

CIA is induced in mice by injecting them with an emulsion of complete Freund's adjuvant and type II collagen.^[2]

In rats, only one injection is needed, but mice are normally injected twice.^[3]

References[edit | edit source]

Collagen-induced arthritis Resources
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Contributors: Prab R. Tumpati, MD