Composite hemangioendothelioma

Composite hemangioendothelioma is a rare type of vascular tumor that is characterized by the presence of both benign and malignant elements. It is a type of hemangioendothelioma, which is a group of vascular neoplasms that can occur in any part of the body.

Clinical Presentation

Patients with composite hemangioendothelioma often present with a painless mass. The tumor can occur at any age, but it is most commonly seen in adults. The most common sites of occurrence are the skin and subcutaneous tissues, but it can also occur in the lymph nodes, bone, and soft tissues.

Pathology

Composite hemangioendothelioma is characterized by the presence of both benign and malignant vascular elements. The benign elements are often composed of capillary hemangioma or cavernous hemangioma, while the malignant elements can include angiosarcoma or epithelioid hemangioendothelioma.

Diagnosis

The diagnosis of composite hemangioendothelioma is often made based on the histological examination of the tumor. Immunohistochemistry can also be used to confirm the diagnosis. The tumor cells are usually positive for endothelial markers such as CD31, CD34, and Factor VIII.

Treatment

The treatment of composite hemangioendothelioma often involves surgical resection of the tumor. Chemotherapy and radiation therapy may also be used in some cases.

Prognosis

The prognosis of composite hemangioendothelioma is variable. Some patients may have a good prognosis with complete surgical resection, while others may have a poor prognosis due to the presence of malignant elements in the tumor.

See Also

• Hemangioendothelioma
• Vascular tumor
• Angiosarcoma
• Epithelioid hemangioendothelioma

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