Compound analgesic

Compound analgesic is a type of analgesic that contains two or more active ingredients used to relieve pain. The combination of different active ingredients in a single dosage form is intended to provide greater pain relief than either drug would provide individually.

Composition

Compound analgesics typically contain a non-opioid analgesic, such as paracetamol (also known as acetaminophen) or a nonsteroidal anti-inflammatory drug (NSAID) like ibuprofen, and an opioid analgesic such as codeine or hydrocodone. Some compound analgesics may also include caffeine or an antihistamine to enhance the pain-relieving effects of the other ingredients.

Mechanism of action

The different active ingredients in a compound analgesic work together to provide pain relief. The non-opioid analgesic works by blocking the production of prostaglandins, chemicals in the body that cause pain and inflammation. The opioid analgesic works by binding to opioid receptors in the brain and spinal cord, blocking the transmission of pain signals to the brain.

Uses

Compound analgesics are used to treat moderate to severe pain that is not adequately controlled by non-opioid analgesics alone. They are commonly used for pain associated with conditions such as arthritis, migraine, and postoperative pain. They may also be used for short-term relief of acute pain, such as pain following dental procedures or injuries.

Side effects

Like all medications, compound analgesics can cause side effects. Common side effects include nausea, vomiting, constipation, and drowsiness. More serious side effects can include respiratory depression, addiction, and overdose, particularly with prolonged use or misuse of the medication.

See also

• Analgesic
• Opioid
• Nonsteroidal anti-inflammatory drug
• Paracetamol
• Ibuprofen
• Codeine
• Hydrocodone