Congenital self-healing reticulohistiocytosis

From WikiMD's Wellness Encyclopedia

Congenital self-healing reticulohistiocytosis (also known as Hashimoto-Pritzker disease) is a rare, benign skin condition. It is characterized by skin lesions that appear at birth or in early infancy and spontaneously regress over a period of weeks to months.

Symptoms[edit | edit source]

The primary symptom of congenital self-healing reticulohistiocytosis is the presence of skin lesions. These lesions are typically red or purple in color and may be found anywhere on the body. They may be solitary or multiple, and they may vary in size. The lesions are not typically associated with any other symptoms, and they spontaneously regress without treatment.

Causes[edit | edit source]

The exact cause of congenital self-healing reticulohistiocytosis is unknown. It is thought to be a disorder of the immune system, specifically the histiocytes, which are a type of white blood cell. Some researchers believe that it may be related to an abnormal response to infection or injury.

Diagnosis[edit | edit source]

Diagnosis of congenital self-healing reticulohistiocytosis is typically made based on the characteristic appearance of the skin lesions. A skin biopsy may be performed to confirm the diagnosis. The biopsy will show an infiltration of histiocytes in the skin.

Treatment[edit | edit source]

As the name suggests, congenital self-healing reticulohistiocytosis typically resolves on its own without treatment. However, in some cases, treatment may be needed to manage symptoms or to speed up the healing process. Treatment options may include topical corticosteroids or other anti-inflammatory medications.

Prognosis[edit | edit source]

The prognosis for individuals with congenital self-healing reticulohistiocytosis is generally good. The skin lesions typically resolve on their own within a few weeks to months, and there are usually no long-term complications. However, in rare cases, the disease may recur.

See also[edit | edit source]

Congenital self-healing reticulohistiocytosis Resources
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Contributors: Prab R. Tumpati, MD