Histiocytosis

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Histiocytosis is a general name for a group of syndromes that involve an abnormal increase in the number of immune cells known as histiocytes. The disease can affect anyone from infants to older adults.

Types of Histiocytosis[edit | edit source]

There are several types of histiocytosis, including:

  • Langerhans cell histiocytosis (LCH): This is the most common type of histiocytosis. LCH can damage skin, bones, and other parts of the body, or form tumors.
  • Non-Langerhans cell histiocytosis: This type includes a variety of conditions that cause histiocytes to build up in certain parts of the body, such as the skin, lymph nodes, and spleen.

Symptoms[edit | edit source]

The symptoms of histiocytosis can vary greatly depending on the type and severity of the condition. They may include:

Diagnosis[edit | edit source]

Histiocytosis is diagnosed through a combination of medical history, physical examination, and laboratory tests. These may include:

Treatment[edit | edit source]

Treatment for histiocytosis depends on the type and severity of the condition. It may include:

Prognosis[edit | edit source]

The prognosis for individuals with histiocytosis varies greatly. Some people may recover completely with treatment, while others may experience long-term complications or disability.

See Also[edit | edit source]

Histiocytosis Resources
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Contributors: Prab R. Tumpati, MD, Dr.T