Conoidasida

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Conoidasida is a subclass of protozoan organisms within the phylum Apicomplexa. This subclass is characterized by the presence of a unique organelle called the conoid, which is a complex of microtubules that forms a cone-like structure at the apex of the cell. The conoid is involved in host cell invasion, a critical process in the life cycle of these parasites.

Taxonomy[edit | edit source]

The subclass Conoidasida is divided into two orders: Gregarinorida and Coccidia. The order Gregarinorida includes parasites that primarily infect invertebrates, while the order Coccidia includes important human and animal pathogens such as Toxoplasma gondii and Plasmodium species, the causative agents of toxoplasmosis and malaria, respectively.

Morphology[edit | edit source]

Conoidasida species are unicellular and possess a complex cell structure. In addition to the conoid, they have specialized secretory organelles called rhoptries, micronemes, and dense granules, which are involved in host cell invasion and modification of the host cell environment.

Life Cycle[edit | edit source]

The life cycle of Conoidasida species typically involves both asexual and sexual reproduction. The asexual phase, or merogony, involves multiple rounds of nuclear division followed by cell division, resulting in the production of many daughter cells. The sexual phase, or gametogony, involves the fusion of two gametes to form a zygote, which then develops into an oocyst. The oocyst eventually releases sporozoites, which are capable of infecting new host cells.

Pathogenesis and Immunity[edit | edit source]

Conoidasida species are responsible for some of the most devastating diseases in humans and animals. The pathogenesis of these diseases is largely due to the ability of these parasites to invade host cells, replicate within these cells, and evade the host immune response. Immunity to Conoidasida infections is complex and involves both the innate and adaptive immune systems.

Treatment and Control[edit | edit source]

Treatment of Conoidasida infections depends on the specific parasite and the severity of the disease. Antiprotozoal drugs are commonly used, but resistance is a growing problem. Control measures include vector control for diseases transmitted by insects, such as malaria, and good hygiene practices for diseases transmitted through contaminated food or water, such as toxoplasmosis. Template:Protozoa-stub Template:Parasites-stub

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Contributors: Prab R. Tumpati, MD