Continuous cell line

Also called immortalised cell lines, this is a population of cells from a multicellular organism which would normally not proliferate indefinitely. However, due to mutation, have evaded normal cellular senescence and instead can keep undergoing division.

Characteristics

• Continuous cell lines are derived from transformed cells
• They persist over a long time
• These can be tumors, and these cells are often able to be subcultured

Grown in vitro

These cells can be grown for prolonged periods in vitro.

Process

The mutations required for immortality can occur naturally or be intentionally induced for experimental purposes.

Benefits

• Immortal cell lines are a very important tool for research into the biochemistry and cell biology of multicellular organisms.
• Immortalised cell lines have also found uses in biotechnology.

Other names

These are also called Immortalised cell line

Stem cells

An immortalised cell line should not be confused with stem cells, that can also divide indefinitely, but form a normal part of the development of a multicellular organism.

Continuous cell line Resources
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