Corino Andrade

Corino de Andrade

Corino de Andrade (1906–2005) was a prominent Portuguese physician and scientist renowned for his discovery of Familial Amyloid Polyneuropathy (FAP), a genetic disorder that predominantly affects the peripheral nervous system. His groundbreaking work in the mid-20th century has had a profound impact on medical research and treatment strategies for hereditary diseases.

Early Life and Education

Corino de Andrade was born in 1906 in Portugal. From a young age, he showed a keen interest in the sciences, which led him to pursue a career in medicine. He completed his medical degree at the University of Porto, where he later became a professor and conducted much of his research.

Career and Research

Throughout his career, Corino de Andrade focused on the study of neurological disorders, with a particular interest in hereditary diseases. His most significant contribution to medicine came in the 1930s and 1940s when he identified and described Familial Amyloid Polyneuropathy (FAP), a disease that was prevalent in certain regions of Portugal.

FAP is characterized by the deposition of amyloid proteins in peripheral nerves and other organs, leading to progressive neuropathy and organ dysfunction. Andrade's identification of the disease's familial nature opened new avenues for research into genetic diseases and their mechanisms.

Legacy

Corino de Andrade's work has left a lasting legacy in the field of medical genetics. His discovery of FAP not only brought attention to a previously unrecognized disease but also paved the way for advancements in genetic testing and therapies. Today, FAP is better understood, and treatments are available to manage the symptoms and slow the progression of the disease, thanks in large part to Andrade's pioneering research.

In recognition of his contributions to medicine, Andrade received numerous awards and honors throughout his lifetime. His work continues to inspire researchers and clinicians in the ongoing fight against genetic disorders.

Death

Corino de Andrade passed away in 2005, leaving behind a legacy of scientific discovery and innovation. His dedication to understanding and treating hereditary diseases has made a significant impact on the lives of many patients and their families.