Isosporiasis

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Isosporiasis
Cystoisospora belli oocyst in epithelial cell (hematoxylin and eosin).jpg
Synonyms N/A
Pronounce N/A
Specialty N/A
Symptoms Diarrhea, abdominal pain, fever, weight loss
Complications Dehydration, malabsorption
Onset 1 to 2 weeks after exposure
Duration Weeks to months, can be chronic in immunocompromised individuals
Types N/A
Causes Cystoisospora belli infection
Risks Immunosuppression, HIV/AIDS, travel to endemic areas
Diagnosis Microscopy, stool examination, PCR
Differential diagnosis Cryptosporidiosis, Giardiasis, Cyclospora infection
Prevention Good hygiene, safe drinking water, proper sanitation
Treatment Trimethoprim/sulfamethoxazole
Medication Antibiotics
Prognosis N/A
Frequency Rare in developed countries, more common in tropical and subtropical regions
Deaths N/A


Isosporiasis is an intestinal disease caused by the parasite Isospora belli. It is a type of coccidiosis, which is a group of diseases caused by coccidian parasites. Isosporiasis is most common in tropical and subtropical regions, but can occur anywhere in the world. It is particularly common in people with HIV/AIDS, but can also affect people with other immunodeficiency conditions.

Causes[edit | edit source]

Isosporiasis is caused by the parasite Isospora belli. The parasite is transmitted through the fecal-oral route, meaning it is spread through contaminated food or water. The parasite forms oocysts, which are resistant to environmental conditions and can survive outside the body for a long time. When a person ingests the oocysts, they hatch in the intestine and cause infection.

Symptoms[edit | edit source]

The symptoms of isosporiasis can vary, but often include diarrhea, abdominal pain, nausea, vomiting, weight loss, and malabsorption. In severe cases, the disease can cause dehydration and electrolyte imbalance. In people with HIV/AIDS, the disease can be severe and chronic.

Diagnosis[edit | edit source]

Diagnosis of isosporiasis is usually made by examining a stool sample under a microscope. The oocysts of Isospora belli can be seen in the stool. In some cases, a biopsy of the intestine may be needed.

Treatment[edit | edit source]

Treatment for isosporiasis usually involves antiparasitic medication, such as trimethoprim/sulfamethoxazole. In severe cases, hospitalization may be needed for rehydration and electrolyte replacement. People with HIV/AIDS may need long-term treatment to prevent recurrence of the disease.

Prevention[edit | edit source]

Prevention of isosporiasis involves good hygiene practices, such as washing hands regularly and avoiding contaminated food and water. In areas where the disease is common, boiling or filtering water can help prevent infection.

See also[edit | edit source]

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Contributors: Prab R. Tumpati, MD