DA-EPOCH-R

DA-EPOCH-R is a chemotherapy regimen used for the treatment of certain types of cancer, including Non-Hodgkin lymphoma and Burkitt lymphoma. The regimen includes the drugs Doxorubicin, Etoposide, Prednisone, Oncovin, Cyclophosphamide, and Rituximab.

Components

The DA-EPOCH-R regimen consists of the following drugs:

• Doxorubicin - An anthracycline antibiotic that works by intercalating DNA.
• Etoposide - A topoisomerase inhibitor that prevents DNA from unwinding, thus inhibiting DNA replication.
• Prednisone - A corticosteroid that reduces inflammation and suppresses the immune system.
• Oncovin (Vincristine) - A vinca alkaloid that inhibits mitosis in metaphase.
• Cyclophosphamide - An alkylating agent that prevents cell division by cross-linking DNA strands.
• Rituximab - A monoclonal antibody that targets the CD20 antigen on B cells.

Treatment Schedule

The DA-EPOCH-R regimen is typically administered in 21-day cycles. The exact schedule and dosage may vary depending on the patient's condition and the type of cancer being treated.

Side Effects

Like all chemotherapy regimens, DA-EPOCH-R can cause side effects. These may include nausea, vomiting, hair loss, fatigue, and neutropenia. Patients should discuss potential side effects with their healthcare provider before starting treatment.

See Also

• Chemotherapy
• Non-Hodgkin lymphoma
• Burkitt lymphoma

DA-EPOCH-R Resources
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