Dapiprazole hydrochloride

Dapiprazole Hydrochloride is a pharmaceutical drug primarily used in the field of ophthalmology. It is an alpha-adrenergic blocking agent, specifically an alpha-1 adrenergic antagonist, which is used to reverse the effects of mydriasis, a condition characterized by the dilation of the pupil.

Pharmacology

Dapiprazole Hydrochloride works by blocking the alpha-1 adrenergic receptors in the smooth muscle of the iris. This action inhibits the effects of sympathetic nervous system stimulation, leading to the constriction of the pupil. The drug is typically administered as eye drops.

Clinical Use

The primary use of Dapiprazole Hydrochloride is to reverse pharmacologically induced mydriasis. This is particularly useful in ophthalmic examinations where mydriasis is induced to facilitate a thorough examination of the retina and other internal structures of the eye. By constricting the pupil, Dapiprazole Hydrochloride helps to reduce light sensitivity and improve visual acuity following the examination.

Side Effects

Common side effects of Dapiprazole Hydrochloride include ocular hyperemia (redness of the eyes), burning or stinging sensation, and blurred vision. These side effects are usually transient and resolve without treatment.

Contraindications

Dapiprazole Hydrochloride is contraindicated in patients with known hypersensitivity to the drug or any of its components. It should be used with caution in patients with severe cardiovascular disease, as it may cause a decrease in blood pressure.

See Also

• Mydriasis
• Ophthalmology
• Alpha-1 adrenergic antagonist