Dementia with Lewy bodies

Dementia with Lewy bodies (DLB) is a type of dementia that is associated with the build-up of a protein called alpha-synuclein in the brain. It is the third most common cause of dementia, after Alzheimer's disease and vascular dementia, accounting for 10-15% of all cases.

Signs and Symptoms[edit | edit source]

Individuals with DLB may exhibit a range of symptoms, including:

Cognitive impairment Fluctuating attention Recurrent visual hallucinations Parkinsonism DLB frequently presents with significant neuropsychiatric symptoms, including hallucinations and delusions. In some cases, these symptoms may precede the onset of cognitive decline.

Causes[edit | edit source]

The exact cause of DLB is unknown. The condition is characterized by the presence of Lewy bodies, which are abnormal aggregates of protein that develop inside nerve cells, impairing their function.

Diagnosis[edit | edit source]

The diagnosis of DLB is often challenging, as it shares symptoms with several other conditions, including Alzheimer's disease and Parkinson's disease. Diagnosis typically involves a thorough medical history, physical examination, cognitive testing, and brain scans.

Treatment[edit | edit source]

There is currently no cure for DLB. Treatment focuses on managing symptoms and may include medications such as cholinesterase inhibitors, antipsychotics, and levodopa.

Prognosis[edit | edit source]

The prognosis for DLB is poor, with a life expectancy of 5-8 years after the onset of symptoms.

Epidemiology[edit | edit source]

DLB is the third most common cause of dementia, accounting for 10-15% of all cases. The condition most commonly affects individuals between the ages of 50 and 85.

References[edit | edit source]

External links[edit | edit source]

Dementia with Lewy bodies at Curlie Dementia with Lewy bodies at Curlie Lewy Body Dementia Association

Dementia with Lewy bodies Resources
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