Demeton

From WikiMD's Food, Medicine & Wellness Encyclopedia

Demeton is an organophosphate compound that was formerly used as an insecticide and acaricide. It is a potent cholinesterase inhibitor, which makes it highly toxic to humans and other mammals.

History[edit | edit source]

Demeton was first synthesized in the 1950s by the German company Bayer AG. It was marketed under various trade names, including "Systox", "Metasystox", and "Omite". However, due to its high toxicity and the availability of safer alternatives, its use has been largely discontinued.

Chemical Properties[edit | edit source]

Demeton is a colorless to yellowish liquid with a garlic-like odor. It is soluble in water and most organic solvents. It is highly volatile, which makes it a potential hazard in the environment.

Toxicity[edit | edit source]

Demeton is a potent inhibitor of cholinesterase, an enzyme that is essential for the proper functioning of the nervous system. Exposure to demeton can cause a range of symptoms, from mild irritation to severe respiratory distress and death. It is also a suspected carcinogen.

Regulation[edit | edit source]

Due to its high toxicity, the use of demeton is heavily regulated. In the United States, the Environmental Protection Agency (EPA) has classified it as a Restricted Use Pesticide (RUP). In the European Union, it is banned under the Biocidal Products Directive.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD