Desert hedgehog (protein)

From WikiMD.com - Food, Medicine & Wellness Encyclopedia

Desert hedgehog (DHH) is a protein that in humans is encoded by the DHH gene. This protein is a member of the hedgehog signaling pathway and plays a key role in the development of the reproductive system and the peripheral nervous system.

Function[edit | edit source]

DHH is a molecule that is part of the hedgehog signaling pathway, a system that is essential for proper embryonic development. This protein is particularly important in the development of the male reproductive system, where it is involved in the formation of the testes and the sperm production process. In the peripheral nervous system, DHH plays a role in the formation of Schwann cells, which are responsible for the myelination of nerve fibers.

Structure[edit | edit source]

The DHH protein is a steroid-like molecule that is secreted by cells. It is composed of two parts: an N-terminal domain that is responsible for signaling activity, and a C-terminal domain that is involved in the processing and secretion of the protein. The N-terminal domain is highly conserved across species, indicating its importance in the function of the protein.

Clinical significance[edit | edit source]

Mutations in the DHH gene can lead to a variety of medical conditions. For example, mutations can cause gonadal dysgenesis, a condition in which the reproductive system does not develop properly. This can lead to infertility and a variety of other reproductive issues. Mutations can also cause neuropathy, a condition that affects the peripheral nervous system and can lead to symptoms such as pain, numbness, and weakness.

See also[edit | edit source]

References[edit | edit source]


Stub icon
   This article is a medical stub. You can help WikiMD by expanding it!


WikiMD
Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Transform your life with W8MD's budget GLP1 injections from $125

W8mdlogo.png
W8MD weight loss doctors team

W8MD offers a medical weight loss program NYC and a clinic to lose weight in Philadelphia. Our W8MD's physician supervised medical weight loss centers in NYC provides expert medical guidance, and offers telemedicine options for convenience.

Why choose W8MD?

Book Your Appointment

Start your NYC weight loss journey today at our NYC medical weight loss, and Philadelphia medical weight loss Call (718)946-5500 for NY and 215 676 2334 for PA

Search WikiMD

Ad.Tired of being Overweight? Try W8MD's NYC physician weight loss.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available. Call 718 946 5500.
Advertise on WikiMD

WikiMD's Wellness Encyclopedia

Let Food Be Thy Medicine
Medicine Thy Food - Hippocrates

Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.

Contributors: Prab R. Tumpati, MD