Devazepide

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Devazepide

Devazepide is a drug that is classified as a cholecystokinin antagonist. It is primarily used in scientific research to explore the role of cholecystokinin in the regulation of appetite and satiety.

Pharmacology

Devazepide acts by blocking the CCK1 receptor, also known as the cholecystokinin A receptor. This receptor is a G protein-coupled receptor that is activated by the hormone cholecystokinin. By blocking this receptor, devazepide inhibits the effects of cholecystokinin, which include stimulation of gallbladder contraction and pancreatic enzyme secretion, as well as regulation of appetite and satiety.

Uses

While devazepide is not used clinically, it is a valuable tool in research. It has been used in studies investigating the role of cholecystokinin in various physiological processes, including digestion, appetite regulation, and the response to stress. In particular, it has been used in studies exploring the potential for cholecystokinin antagonists to be used in the treatment of obesity.

Side Effects

As a research tool, devazepide is not typically administered to humans, so its side effect profile is not well established. However, in animal studies, it has been shown to cause a decrease in food intake and body weight.

See Also

• Cholecystokinin
• CCK1 receptor
• G protein-coupled receptor
• Appetite
• Satiety