Didesmethylescitalopram
Didesmethylescitalopram is a pharmacological compound related to escitalopram, a commonly prescribed selective serotonin reuptake inhibitor (SSRI). It is a primary metabolite of escitalopram, formed in the body during the metabolic breakdown of the drug.
Chemistry[edit | edit source]
Didesmethylescitalopram is a stereoisomer of the parent compound, escitalopram. It is formed by the removal of two methyl groups from the escitalopram molecule. This process, known as demethylation, is a common metabolic pathway for many drugs and other xenobiotics.
Pharmacology[edit | edit source]
As a metabolite of escitalopram, didesmethylescitalopram is thought to contribute to the overall therapeutic effect of the drug. However, its specific pharmacological activity is not well understood. It is known to be less potent than escitalopram in inhibiting the reuptake of serotonin, but it may have other pharmacological effects that contribute to the overall action of the drug.
Clinical significance[edit | edit source]
The clinical significance of didesmethylescitalopram is primarily related to its role as a metabolite of escitalopram. The levels of didesmethylescitalopram in the body can be influenced by various factors, including the dose of escitalopram, the individual's metabolic rate, and the presence of other drugs that can affect the metabolism of escitalopram. Monitoring the levels of didesmethylescitalopram in the body can provide useful information about the individual's response to escitalopram treatment.
See also[edit | edit source]
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