Piperazine
(Redirected from Diethylenediamine)
Piperazine is an organic compound that consists of a six-membered ring containing two nitrogen atoms at opposite positions in the ring. It is a heterocyclic amine and is commonly used in the chemical industry and in medicine.
Chemical Structure and Properties[edit | edit source]
Piperazine has the chemical formula C₄H₁₀N₂. It is a cyclic compound with the molecular structure of a six-membered ring containing two nitrogen atoms. The nitrogen atoms are located at the 1 and 4 positions of the ring, making it a 1,4-diazacyclohexane. Piperazine is a colorless solid that is soluble in water and has a slightly alkaline taste.
Synthesis[edit | edit source]
Piperazine can be synthesized through several methods, including the hydrogenation of pyrazine or the reaction of ethylene diamine with diethylene glycol. It can also be produced by the cyclization of 1,2-diaminoethane.
Uses[edit | edit source]
Medical Applications[edit | edit source]
Piperazine is widely used as an anthelmintic agent to treat parasitic worm infections such as ascariasis and enterobiasis. It works by paralyzing the worms, which are then expelled from the body through natural processes.
Industrial Applications[edit | edit source]
In the chemical industry, piperazine is used as an intermediate in the manufacture of various pharmaceuticals, resins, and other chemicals. It is also used as a corrosion inhibitor in water treatment processes and as a curing agent for epoxy resins.
Derivatives[edit | edit source]
Several derivatives of piperazine are used in medicine and industry. These include:
- Diethylcarbamazine - used to treat filariasis.
- Fluphenazine - an antipsychotic medication.
- Ciprofloxacin - a broad-spectrum antibiotic.
Safety and Toxicity[edit | edit source]
Piperazine can cause side effects such as nausea, vomiting, and diarrhea when used in medical treatments. In industrial settings, it should be handled with care as it can be irritating to the skin and eyes. Proper safety measures, including the use of personal protective equipment, should be followed when handling piperazine.
See Also[edit | edit source]
References[edit | edit source]
External Links[edit | edit source]
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
WikiMD's Wellness Encyclopedia |
Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD