Dimethyldienolone

From WikiMD.com Medical Encyclopedia


Overview[edit | edit source]

Dimethyldienolone is a synthetic anabolic steroid and a derivative of nandrolone. It is known for its potent androgenic and anabolic effects. Dimethyldienolone is not approved for medical use and is primarily encountered in the context of performance-enhancing drugs.

Chemical Structure[edit | edit source]

Chemical structure of Dimethyldienolone

Dimethyldienolone is chemically classified as a 19-nortestosterone derivative. Its structure is characterized by the presence of a 17_-methyl group and a 9,11-diene configuration, which contribute to its high potency and resistance to metabolic breakdown.

Mechanism of Action[edit | edit source]

Dimethyldienolone exerts its effects by binding to the androgen receptor, which leads to the activation of gene transcription and subsequent protein synthesis. This results in increased muscle mass and strength, as well as other androgenic effects such as the development of male secondary sexual characteristics.

Pharmacokinetics[edit | edit source]

The pharmacokinetics of Dimethyldienolone involve its absorption, distribution, metabolism, and excretion. Due to its methylation at the 17_ position, it is orally active and resistant to hepatic metabolism, allowing it to maintain its activity when administered orally.

Side Effects[edit | edit source]

The use of Dimethyldienolone can lead to a range of side effects, particularly due to its androgenic properties. These may include:

Legal Status[edit | edit source]

Dimethyldienolone is classified as a controlled substance in many countries due to its potential for abuse and adverse health effects. It is banned by most sports organizations and is included in the list of prohibited substances by the World Anti-Doping Agency.

Related Compounds[edit | edit source]

Dimethyldienolone is related to other anabolic steroids such as nandrolone, trenbolone, and methandrostenolone. These compounds share similar mechanisms of action and effects but differ in their chemical structure and potency.

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Contributors: Prab R. Tumpati, MD