Disaccharidase

Disaccharidase is a type of enzyme that is responsible for breaking down certain types of sugars known as disaccharides into simpler sugars called monosaccharides. These enzymes are found in the small intestine and play a crucial role in the digestion of carbohydrates.

Function

Disaccharidases are located on the brush border membrane of the enterocytes lining the small intestine. They hydrolyze disaccharides into monosaccharides which can then be absorbed by the body. The three main types of disaccharidases are sucrase, lactase, and maltase.

Sucrase

Sucrase is the enzyme that breaks down sucrose (table sugar) into glucose and fructose, which can then be absorbed into the bloodstream.

Lactase

Lactase is responsible for the digestion of lactose, the sugar found in milk. It breaks down lactose into glucose and galactose.

Maltase

Maltase breaks down maltose (malt sugar) into two glucose molecules.

Clinical significance

Deficiency in any of these enzymes can lead to a variety of digestive disorders. For example, a deficiency in lactase can lead to lactose intolerance, a condition where the body is unable to fully digest lactose, leading to symptoms such as bloating, diarrhea, and gas.

See also

• Digestive enzyme
• Carbohydrate metabolism
• Monosaccharide
• Digestion

References

Disaccharidase Resources
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