Maltase

Maltase is an important enzyme that plays a crucial role in the digestion process. It is specifically responsible for the hydrolysis of maltose to glucose. Maltase is produced by the cells lining the small intestine.

Function

Maltase catalyzes the final step in the digestion of carbohydrates. It breaks down the disaccharide maltose into two units of glucose, which can then be absorbed into the bloodstream for use by the body's cells. This process is essential for providing the body with the energy it needs to function.

Structure

Maltase is a protein enzyme that is composed of 496 amino acids. It has a molecular weight of approximately 54,000 Daltons. The enzyme has two active sites, each of which can bind to a molecule of maltose and catalyze its hydrolysis.

Clinical significance

Deficiency in maltase can lead to malabsorption of maltose and other similar carbohydrates, resulting in diarrhea and abdominal pain. This condition is known as congenital sucrase-isomaltase deficiency (CSID). CSID is a rare genetic disorder that affects the digestion of certain sugars.

See also

• Disaccharidase
• Lactase
• Sucrase

References

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