Doxibetasol

Doxibetasol is a synthetic glucocorticoid used primarily in the treatment of dermatological conditions. It is a potent corticosteroid, classified as a "super-high potency" topical steroid, and is used for the relief of inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.

Pharmacology

Doxibetasol works by reducing the actions of chemicals in the body that cause inflammation, redness, and swelling. It is a synthetic corticosteroid, a class of primarily synthetic steroids used as anti-inflammatory and anti-pruritic agents. The exact mechanism of action of doxibetasol is not known, but it is believed to act by inducing phospholipase A2 inhibitory proteins, which control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes.

Uses

Doxibetasol is used to treat a variety of skin conditions, including psoriasis, eczema, and allergic reactions. It is also used to treat rashes, itching, and swelling caused by certain skin conditions. It is typically applied topically, in the form of a cream or ointment, and is often used in combination with other medications.

Side Effects

Like all medications, doxibetasol can cause side effects. Common side effects include skin irritation, burning, and dryness. More serious side effects can include skin thinning, stretch marks, and skin discoloration. In rare cases, it can cause systemic side effects, such as weight gain, puffiness in the face, and fatigue.

Precautions

Before using doxibetasol, patients should inform their healthcare provider if they have any allergies, or if they have a history of poor blood circulation, immune system problems, or certain skin conditions. It should not be used on the face, underarms, or groin area unless directed to do so by a healthcare provider.

See Also

• Corticosteroid
• Dermatology
• Psoriasis
• Eczema